News

Pathology of Non-Alcoholic Fatty Liver Disease

Post Date : 01/01/2015

Volume 10, Issue 1, January 2015

Dr. Anthony W.H. Chan

Associate Professor Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong

Introduction

Non-alcoholic fatty liver disease (NAFLD) is a serious global health problem and associated with over-nutrition and its related metabolic risk factors including central obesity, glucose intolerance, dyslipidaemia and hypertension. It is the most common metabolic liver disease worldwide and its prevalence in most Asian countries is similar to that in the States, Europe and Australia. About 10-45% of Asian population have NAFLD. With “westernized” sedentary lifestyle, the prevalence of NAFLD in general urban population in the mainland China is about 15%. NAFLD is even more prevalent in Hong Kong. Our recent study demonstrated...

College Newsletter Volume23, Issue 2, November 2014

Post Date : 02/11/2014

The 23:2 edition of College Newsletter is now ready: /newsletter 23:2

Index of this issue:

  • Message from the President
  • Featured article: Should we be thinking about revalidation or recertification of pathologists
  • Topical Update: Molecular Classification and Genetic Alterations of Diffuse Large B-cell Lymphoma
  • Report on Research Project funded by Chan Woon Cheung Education and Research Fund
  • Out of the Whitecoat: My Sake Journey
  • Obituary: Dr Rina WONG Kwai Ying
  • Obituary: Dr Joanna HO Chor Ying
  • Membership Examination and Fellowship Assessment results
  • Programme of the 23rd Annual General Meeting: 29/11/2014
  • International Pathology Day Exhibition: 5/11/2014 - 11/11/2014

Results of College Exam 2014 (Council Meeting 17 September 2014)

Post Date : 17/09/2014

Fellowship Assessment:
Exam No. Result
AN14302 Fail
AN14304 Fail
AN14306 Fail
AN14307 Fail
AN14308 Pass
AN14309 Pass
AN14311 Pass
AN14313 Pass
AN14315 Pass
E14211 Fail
E14212 Pass
E14214 Fail
E14215 Pass
E14216 Fail

 

...

Result of College Exam 2014 (Council Meeting 28 July 2014)

Post Date : 28/07/2014

Fellowship Assessment:
Exam No. Result
E14210 Fail
E14213 Fail

Membership Examination:

Exam No. Result
E14107 Fail

Molecular Classification and Genetic Alterations of Diffuse Large B-cell Lymphoma

Post Date : 01/07/2014

Volume 9, Issue 2, July 2014

Dr CHOI Wai Lap

Department of Clinical Pathology Tuen Mun Hospital

Introduction

Diffuse large B-cell lymphoma (DLBCL) is the commonest subtype of non-Hodgkin lymphoma, accounting for about 30% to 40% of newly diagnosed non-Hodgkin lymphoma worldwide and in Hong Kong. DLBCL is heterogeneous in clinical presentation, morphology, immunophenotype, cytogenetics and prognos is. In the WHO Classification of Tumours of the Haematopoietic and Lymphoid Tissues published in 2008, several specific clinicopathological entities of DLBCL have been recognized, while leaving the rest to DLBCL, not otherwise specified, which is by far the most prevalent entity among the large B-cell lymphomas. In the following discussion, the term DLBCL will be used interchangeably with DLBCL, not otherwise specified.

...

College Newsletter Volume 23, Issue 1, May 2014

Post Date : 26/05/2014

College Newsletter Volume 23, Issue 1, May 2014

The 23:1 edition of College Newsletter is now ready: newsletter 23:1

Index of this issue:

  • Message from the President
  • The 22nd Annual General Meeting 2013 and the 22nd T.B. Teoh Foundation Lecture
  • Membership Lists of Council, Committees and Boards 2014-2015
  • The 9th Trainee Presentation Session
  • Topical Update: Thyroid Dyshormonogenesis
  • College Takes the Lead in Public Issues
  • Out of the Whitecoat: Bridge
  • Fellows¡¦ Laurels
  • Announcement from the Education Committee
  • Announcement from the Training and Examinations Committee

Result of College Supplementary Autopsy Exam 2014 (Council meeting 26 Feb 2014)

Post Date : 26/02/2014
Exam No. Result
SE13101 Fail
SE13201 Fail

 

Thyroid Dyshormonogenesis

Post Date : 01/01/2014

Volume 9, Issue 1, January 2014

Dr YUEN Yuet Ping

Department of Chemical Pathology Prince of Wales Hospital

Introduction

Congenital hypothyroidism (CH) is an important preventable cause of mental retardation. To prevent irreversible brain damages caused by hypothyroidism, sufficient doses of thyroxine should be started within a few weeks after birth.(1) Since neonates with CH have no obvious or minimal clinical manifestations, biochemical screening in the newborn period has become the best public health strategy for early detection of affected neonates. In Hong Kong, a territory-wide screening programme for CH was started in 1984.(2) Cord blood samples are collected immediately after birth for measurement of thyroid stimulating hormone (TSH) by a single laboratory dedicated for newborn screening. The incidence of CH in...

Epidemiology of Cervical Human Papillomavirus Infection in Hong Kong: Implications on Preventative Strategy

Post Date : 15/07/2013

Volume 8, Issue 2, July 2013

Prof. Paul KS Chan

Professor, Department of Microbiology, Prince of Wales Hospital The Chinese University of Hong Kong

Introduction

The family Papillomaviridae is comprised of a large group of viruses found in many mammalian species. Infection with papillomaviruses can be asymptomatic or results in the development of benign or malignant neoplasia. Cervical cancer is the most important consequence, in terms of disease burden, of human papillomavirus (HPV) infection. To date, the genomic sequences of more than 150 HPV types have been characterized. Of these, more than 40 types can infect the female genital tract, and at least 15 types are epidemiologically linked to cervical cancer. Over the last few years, there has been a vast increase in using HPV DNA detection as an adjunctive or primary...

Laboratory Testing For Anti-NMDAR In Autoimmune Encephalitis: The HSSA- Pathology Queensland Experience

Post Date : 01/01/2013

Volume 8, Issue 1, January 2013

Bob Wilson MSc, FFS(RCPA), Kerri Prain, BSc, David Gillis, FRCPA FRACP FFS(RCPA) and Richard Wong GDM FRCPA FRACP FRCP.

Division of Immunology, Central Laboratory, HSSA-Pathology Queensland, Royal Brisbane and Women’s Hospitals, Herston, Brisbane, 4061, Australia.

Introduction

The spectrum of antibodies against intracellular, cell surface and synaptic neuronal antigens has expanded rapidly in recent years. The antigenic targets include ion channels, receptors involved in neurotransmission across synapses and proteins associated with them. There are now more than twenty anti-neuronal antibodies detected in association with neurological diseases. These antibodies may be associated with underlying malignancies and are commonly referred to as paraneoplastic antibodies (PNAs). Many PNAs have...